How common is the follow up gap?
Very common. In Tufts CSDD's survey, nearly 30% of physicians and 45% of nurses reported never receiving initial or follow up contact from site staff after making a referral (Tufts CSDD via Applied Clinical Trials). Physicians refer a median of five patients into trials per year (Getz). A site that goes silent after the first one rarely gets a second.
What does a good follow up schedule look like?
- Confirm the referral within two business days: thank the physician and name the coordinator handling it.
- Report the screening outcome once it is known: screened, not eligible, or declined.
- Report enrollment if the patient randomizes, and how the site will coordinate with the physician's ongoing care.
- Close the loop when the patient completes or leaves the study.
- Share results when the study publishes them.
What should you do when a referred patient is not eligible?
Tell the physician, and say why in general terms, such as a lab value outside the range or a disallowed medication. That teaches them your criteria faster than any letter and makes their next referral more likely to qualify.
How do you follow up with physicians who have not referred yet?
A single letter arrives on a busy day. Follow up by email and LinkedIn over the following weeks, and prioritize physicians who showed interest. A unique QR code on each letter shows which physicians scanned it, so coordinators can call the interested ones first instead of working an entire list.
Why does follow up matter beyond one referral?
Patients expect it: 95% of CISCRP respondents said it is important for their regular doctor to be aware of studies (CISCRP). Physicians who see that a site treats their patients well become repeat referrers across studies, which makes each new study faster to launch.
Related: what physicians need to know before referring.
Get your study in front of the right local physicians
TrialNotice builds a physician referral pipeline around one active study. We identify relevant local physicians within driving distance of your site, send study aligned direct mail, follow up by email and LinkedIn, track engagement with recipient level QR codes, and route warm responses into your site team's workflow.
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