TrialNotice is an outbound recruitment service for clinical trial sites. We get clinical trials in front of local referring physicians through a coordinated multi-channel pipeline: physician discovery, study-aligned outreach by mail, email, and LinkedIn, per-recipient QR tracking, and integration into the trial site's existing CTMS, CRM, and reporting stack.
Step 1: We map every relevant physician within driving distance of the trial site. Each practice is matched by NPI specialty taxonomy, verified, and enriched with addresses and contact details. The output is a list of every physician who could plausibly refer a matching patient — typically several hundred per metro area for a single trial.
Step 2: We turn the study into a list of matching physicians. The matching engine ingests the study from ClinicalTrials.gov, extracts phase, indication, patient profile, and inclusion/exclusion criteria, matches taxonomy and specialty, finds nearby practices via Google Places, fetches verified emails and addresses, and verifies and scores the data. The output is an outreach-ready physician list per enrollment site.
Step 3: We send study-aligned, professionally written outreach to each matched physician with recipient-level QR tracking and structured, multi-channel follow-up. Letters are mailed via USPS First Class with branded envelopes and unique QR codes. Email and LinkedIn follow-up runs over a 14-day cadence.
Step 4: Every scan, every reply, tracked per physician. Per-letter QR scans, email opens, LinkedIn responses, and SDR call outcomes are logged in real time. Live signals route straight to the study coordinator's dashboard with the full engagement history per physician.
Step 5: The conversation does not stop after the scan. Email, LinkedIn, SDR calls, and social outreach run in coordinated sequence. Each reply is captured, logged, assigned to a team owner, and converted into the next action.
Step 6: Plugged into the tools your site already runs on. Warm referrals route into the site's CTMS (RealTime eClinical, Veeva Vault CTMS, Florence eBinder, Advarra OnCore), CRM (Salesforce, HubSpot, REDCap), reporting and workflow tools (Google Sheets, Slack, Airtable), and outreach channels (USPS, FedEx, UPS, LinkedIn, Twilio SMS) — without the team changing how they work.
84% of patients say they would consider participating in a clinical trial if their physician recommended it (CISCRP — Center for Information & Study on Clinical Research Participation).
94.3% of patients say it is important that their physician be aware of clinical studies running in their community (CISCRP 2017 Perceptions & Insights, 11,719 of 12,427 respondents).
71% of patients who have not yet participated in a trial say they would be willing to (CISCRP 2017, 12,500 individuals surveyed globally).
80% of patients are willing to join clinical research, with the location of the trial site the deciding factor (CISCRP 2015 patient survey).
More than 80% of clinical trials miss their original patient recruitment timeline (Tufts Center for the Study of Drug Development).
$1.2 billion is spent annually in the United States on patient recruitment for clinical trials (CISCRP Perceptions & Insights Study 2021).
The largest underused lever in patient recruitment is the local referring physician. Patients trust their doctor. Doctors recommend what they know about. The bottleneck is awareness, not willingness — and that is the gap TrialNotice closes.
Clinical trial sites, principal investigators, study coordinators, sponsor-side recruitment teams, and CROs working on Phase 2 and Phase 3 trials in any therapeutic area.
Email: info@trialnotice.com. Address: 3325 S University Dr, Suite 209, Davie, FL 33328, United States.
Falling short on patient recruitment puts your study at risk. We build a targeted, multi-channel physician outreach engine that scales efficiently.
Each plan is priced for one active study. We continuously work the selected target prospect pool with two letters per prospect per month, plus email, LinkedIn, QR tracking, CRM access, notifications, calendar integration, and hands-on support.
Instead of starting with broad media spend, TrialNotice helps your site activate nearby referring physicians around each active study.
100 target prospects under active monthly outreach
4-month renewable contract
500 target prospects under active monthly outreach
4-month renewable contract
1,000 target prospects under active monthly outreach
4-month renewable contract
Clinical trial sites often need more than patient advertising. They need local physicians who know the study exists, understand which patients may fit, and have a simple way to refer interest back to the site.
TrialNotice identifies matched local physicians within driving distance of the enrollment site, then works that prospect pool with study-aligned letters, email, LinkedIn follow-up, QR tracking, and coordinator-ready handoff.
We start with the study details, therapeutic area, patient profile, and geography. Then we map relevant physicians and practices, so outreach is pointed at people who can realistically refer patients.
It is a structured process for finding matched local physicians, sending study-specific outreach, tracking engagement, and routing warm responses into the site team's workflow, CRM, calendar, or coordinator dashboard.
Broad media can create awareness, but it can also create screening waste. TrialNotice focuses on local physician awareness, referral activation, and tracked conversations with practices near the site.
Each TrialNotice plan is priced for one active study. The selected prospect pool stays under active monthly outreach, with two letters per prospect per month, email and LinkedIn follow-up, recipient-level QR tracking, CRM access, notifications, calendar integration, and full coordinator support.
TrialNotice is built for research sites that need more qualified referral activity around an active study, especially from local physicians and practices near the enrollment site.
Clinical trial sites get more physician referrals by making local physicians aware of the study, giving them a clear patient profile, and giving the practice a simple next step. TrialNotice builds that pipeline by mapping matched physicians, sending study-aligned direct mail, following up by email and LinkedIn, and tracking every response back to the site team.
A research site can increase patient flow by combining patient-facing recruitment with physician referral activation. TrialNotice focuses on the physician side: reaching local doctors who already see patients in the relevant therapeutic area and turning their awareness into tracked referral opportunities.
Yes, direct mail can help when it is specific, study-aligned, and paired with follow-up. TrialNotice uses professionally written letters, recipient-level QR tracking, and coordinated email and LinkedIn outreach so the letter becomes part of a measurable physician engagement sequence.
A physician referral pipeline is the system that identifies relevant local physicians, sends them study-specific outreach, tracks engagement, captures replies, and routes warm physician interest into the research site's CRM, CTMS, calendar, or coordinator workflow.
No. TrialNotice is designed to plug into the tools a site already uses. Warm responses, QR scans, replies, and follow-up signals can route into the site's existing CRM, CTMS, reporting tools, calendar workflow, or coordinator handoff process.
Each plan is priced for one active study and includes the selected monthly target prospect pool, two letters per prospect per month, email and LinkedIn follow-up, QR codes, notifications, CRM access, calendar integration, direct mail costs, email infrastructure, AI and API usage, and support for the site team.
TrialNotice is not a generic ad agency, a mailing vendor, or a post office. It is a physician referral outreach system for clinical research sites that need local physicians to know about an active study and understand how to refer potential patients.
The TrialNotice model is built around a simple recruitment reality: patients often trust their physicians, and local physicians can only recommend studies they know about. The links below point to current or 2025+ research and industry context around clinical trial participation, enrollment performance, recruitment challenges, and patient engagement.
Contact us now and we will help you understand the physician outreach footprint around your active study.
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